Detection of Leprosy in Ancient Human Skeletal Remains by Molecular Identification of Mycobacterium leprae
نویسندگان
چکیده
منابع مشابه
Detection and Strain Typing of Ancient Mycobacterium leprae from a Medieval Leprosy Hospital
Nine burials excavated from the Magdalen Hill Archaeological Research Project (MHARP) in Winchester, UK, showing skeletal signs of lepromatous leprosy (LL) have been studied using a multidisciplinary approach including osteological, geochemical and biomolecular techniques. DNA from Mycobacterium leprae was amplified from all nine skeletons but not from control skeletons devoid of indicative pat...
متن کاملUse of 18 and 36 kDa antigens of Mycobacterium Leprae for detection of this microorganism in Iranian Leprosy patients by PCR
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متن کاملBioarchaeology: Scientific Studies of Archaeological Human Skeletal Remains
Bioarchaeology is an interdisciplinary academic specialty, which through the scientific analysis and interpretation of archaeological human skeletal remains, bridges the link between the biological sciences, medicine, anthropology and social sciences. The cornerstone of bioarchaeology is the interaction between culture and human biology. Since the study of people and ancient societies is one of...
متن کاملImmunological Identification of Foot-pad Isolates as Mycobacterium Leprae by Lepromin Reactivity in Leprosy Patients
Lepromin, a product containing Mycobacterium leprae from patients' tissues, fails to elicit skin reactions in lepromatous patients; this non-reactivity was utilized as a means of identifying the mycobacterium isolated in mouse foot-pads from leprosy patients. To do this a suspension of acid-fast bacilli prepared from mouse foot-pads infected with a typical isolate was compared to human lepromin...
متن کاملAutoimmunity to Tropomyosin-Specific Peptides Induced by Mycobacterium leprae in Leprosy Patients: Identification of Mimicking Proteins
Citation: Singh I, Yadav AR, Mohanty KK, Katoch K, Sharma P, Pathak VK, Bisht D, Gupta UD and Sengupta U (2018) Autoimmunity to Tropomyosin-Specific Peptides Induced by Mycobacterium leprae in Leprosy Patients: Identification of Mimicking Proteins. Front. Immunol. 9:642. doi: 10.3389/fimmu.2018.00642 autoimmunity to Tropomyosinspecific Peptides induced by Mycobacterium leprae in leprosy Patient...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2000
ISSN: 1943-7722,0002-9173
DOI: 10.1093/ajcp/114.3.428